Synthesis and Biological Activities of Novel Analogues of Phthalamide Containing Acylurea and Acylthiourea
Year: 2015
Type: article
Abstract: In order to find novel and efficient insecticides targeting at the ryanodine receptor, a series of novel compounds containing acylurea and acylthiourea, referring to moieties of flubendiamide and diflubenzuron, were designed and synthesized.Their structures were characterized by 1 H NMR, HRMS and X-ray diffraction.The insectical activities showed that the introducing of acylurea and acylthiourea bridges decreased the acitivity.Compound 7d showed 50% activity at the concentration of 10 mg/L.In addtion, some structures showed moderate antifungal activities.Compound 8f displayed 75.0%, 87.5% and 84.6% antifungal activities against Botryosphaeria dothidea, Rhizoctonia cerealis and Fusarium fujikuroi.
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W2332828752