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A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling

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Year: 2016
Type: article
Source: Cell
DOI: 10.1016/j.cell.2016.03.045
Authors: Sai Krishna Athuluri-Divakar, Rodrigo Vasquez-Del Carpio, Kaushik Dutta, Stacey J. Baker, Stephen C. Cosenza, Indranil Basu, Yogesh K. Gupta, M.V. Ramana Reddy, Lynn Ueno, Jonathan R. Hart, Peter K. Vogt, David Mulholland, Chandan Guha, Aneel K. Aggarwal, E. Premkumar Reddy
Institutions: Icahn School of Medicine at Mount Sinai, New York Structural Biology Center, Albert Einstein College of Medicine, Yeshiva University, Scripps Research Institute
Language: English

Topic: Protein Kinase Regulation and GTPase Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, National Center for Research Resources
Awards: G1056585961, G2592308081, The Antisense Transcriptome and the Epigenetics of Cancer., Targeting Mitotic Kinases Inhibitors for Cancer Therapy, P3K, Retroviral Oncogene and Homolog of PI 3-Kinase, G455371571, G7017544567
OpenAlex ID: W2339828620
FWCI: 18.82
Cites: 56
Cited by: 277
Related to: 10
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