Work

Theragnostic ultrasound using microbubbles in the treatment of prostate cancer

Year: 2016

Type: review

Abstract: The use of gas-filled microbubbles in perfusion monitoring as intravascular ultrasound contrast agents has recently become more common. Additionally, microbubbles are employed as carriers of pharmaceutical substances or genes. Microbubbles have great potential to improve the delivery of therapeutic materials into cells and to modify vascular permeability, causing increased extravasation of drugs and drug carriers. Prostate cancer is the most common neoplasm in Europe and America, with an incidence twice to three times that of lung and colorectal cancer. Its incidence is still rising in Asian countries, including Japan and Korea. In this review, we present current strategies regarding the synthesis of microbubbles with targeted ligands on their surfaces, with a focus on prostate cancer.

Source: ULTRASONOGRAPHY

DOI: 10.14366/usg.16006

Authors: Hak Jong Lee, Young Il Yoon, Yun Jung Bae

Institutions: Seoul National University, Seoul National University Bundang Hospital

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Research Foundation of Korea