Work

Biomechanical parameter determination of scaffold-free cartilage constructs (SFCCs) with the hyperelastic material models Yeoh, Ogden and Demiray

Year: 2015

Type: article

Abstract: The biomechanical properties are crucial indicators for the functional characterization of cartilaginous tissue. In this contribution native articular cartilage and three-dimensional scaffold-free cartilage constructs (SFCCs) are characterized by hyperelastic material models (Yeoh, Ogden and Demiray). SFCCs were developed for the therapy of damaged articular cartilage. The normalized error (NE) of fit and experiment is in the range of 0.04 and 0.13. The material model Yeoh with two parameters yields the best fit. The stress-like parameterc 20 is 0.489 MPa for native cartilage, 0.120 MPa and 0.041 MPa for SFCCs produced from mesenchymal stem cells and chondrocytes, respectively. The significance of the fits and the derived parameters are presented and evaluated.

Source: Current Directions in Biomedical Engineering

DOI: 10.1515/cdbme-2015-0106

Authors: T. Reuter, I. Ponomarev

Institution: Research Centre of Medical Technology and Biotechnology

Language: English

Topic: Elasticity and Material Modeling

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2346148385

FWCI: 0.145

Cites: 8

Cited by: 5

Related to: 10