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A case of primary cardiac lymphoma with superior vena cava syndrome and sinus bradycardia

Year: 2009
Type: article
Study design: Case Report
Abstract: We report a case of primary cardiac lymphoma (PCL) with superior vena cava syndrome and sinus bradycardia. PCL accounts for 1.3% of primary cardiac tumors. The clinical manifestations of PCL are mainly pericardial effusion, heart failure, and atriculoventricular block. Primary cardiac lymphoma has poor prognosis; therefore, early diagnosis and treatment are recommended for better outcome. We report a case of PCL in a 71-year-old woman who had worsening dyspnea and facial edema. Initial electrocardiography showed sinus bradycardia. Color Doppler imaging and chest computed tomography revealed a large right-atrial mass that extended to the superior and inferior vena cava, with pericardial and pleural effusion. The tumor was partially resected. The pathological diagnosis was diffuse large B-cell lymphoma with expression of CD20. After tumor resection, the patient was treated by systemic chemotherapy with CHOP (cyclosphosphamide, doxorubicin, vincristine, and prednisone) plus rituximab. (Korean J Med 77:S445-S450, 2009)
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $500
OpenAlex ID: W2390961353
FWCI: 0.217
Cites: 11
Cited by: 1
Related to: 10