Microscopic polyangiitis presenting with painless anal bleeding
Year: 2009
Type: article
Study design: Case Report
Abstract: Microscopic polyangiitis (MPA) is a systemic vasculitis that is characterized by small-vessel involvement histologically. Although MPA is primarily associated with necrotizing and crescentic glomerulonephritis and pulmonary capillaritis, it often has gastrointestinal (GI) involvement. The most frequent GI symptom in MPA is abdominal pain of an ischemic nature, while GI bleeding is rare. We report a case of MPA that presented with painless anal bleeding, which was initially misdiagnosed as an internal hemorrhoid. The surgical specimen of the anus showed vasculitis of small arteries with fibrinoid necrosis and the renal biopsy showed necrotizing glomerulonephritis with tubular atrophy. To our knowledge, this is the first reported case of anal involvement in MPA. (Korean J Med 77:S1337-S1341, 2009)
Authors: Seung Woo Han, Hyuck Yong Kwon, Jong Kyu Kwon, Jin Woo Choi, Kyung Sook Lee, Kyung Rak Sohn, Gun Woo Kim
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $500
OpenAlex ID: W2398468554