Year: 1965
Type: article
Abstract: The Koenig-Knorr reaction of tri-O-acetyl-1-bromo-1-deoxy-α-D-glucopyranuronic acid and 2-chloroethanol was found to produce three compounds; 2-chloroethyl tri-O-acetyl-β-D-glucopyranosiduronic acid (II), 2-hydroxyethyl (2-chloroethyl tri-O-acetyl-β-D-glucopyranosid) uronate (V), and 1-O-(2-chloroethyl tri-O-acetyl-β-D-glucopyranosiduronoyl) tri-O-acetyl-β-D-glucopyranuronic acid (VIII). Reaction of tetra-O-acetyl-D-glucopyranuronic acid and acetylated halogen-sugar derivatives in acetone, in the presence of silver carbonate, afforded the corresponding ester-type disaccharides and examinations were made on the stability of these compounds in aqueous ammonia.
Source: YAKUGAKU ZASSHI
Authors: Atsushi Momose, Ryohei Iida, Yoshihiro Nitta
Institution: Chugai Pharmaceutical Co., Ltd. (Japan)
Language: Japanese
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W2460098968