Work

Hybrid Alginate‐Based Cryogels for Life Science Applications

Year: 2016

Type: article

Abstract: This work presents a novel route toward porous scaffolds for tissue engineering and regenerative medicine (TERM) applications. Hybrid cryogels with gelatin, gellan gum, carboxymethylcellulose, and lignin were prepared by a two‐step process. Textural properties of the cryogels were analyzed by SEM and micro‐computed tomography. The results indicated that rapid freezing retained sample shape and yielded macroporous materials. The mechanical properties of the cryogels were characterized in compression mode. Cytotoxicity studies indicated that the hybrid‐alginate cryogels did not present cytotoxicity and have the potential to be used in TERM.

Source: Chemie Ingenieur Technik

DOI: 10.1002/cite.201600096

Authors: Alexandre Barros, Sakeena Quraishi, Marta Martins, Pavel Gurikov, Raman Subrahmanyam, Irina Smirnova, Ana Rita C. Duarte, Rui L. Reis

Institutions: 3B's Research Group, University of Minho, Hamburg University of Technology

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2512334232

FWCI: 0.783

Cites: 49

Cited by: 27

Related to: 10