Proposal for a new site to insertion of dental implants for osseointegration test: Research methodology
Year: 2015
Type: article
Abstract: Background: The objective of this paper was to present a methodology for osseointegration in rat mandibles. Materials and Methods:A total of 16 Wistar male rats with 400 g were undergone to anesthesia, and then blunt instruments were used to expose the alveolar inferior nerve.Once the nerve canal was emptied, one implant (2.2 mm × 4 mm) was installed near the mandibular canal.The animals were sacrificed within the experimental period of 15 (n = 8) and 30 (n = 8) days.The histomorphometric analysis included both boneimplant contact and bone area. Results:In a comparison of the variables between 15 and 30 days, there were differences in bone maturation (Student's parametric test for independent samples -P < 0.05).In addition, the technique was shown to be reproducible and performed at a lower cost compared with histological studies involving other animals.Conclusion: This specific technique of placing implants into the mandibles of rats is a viable alternative in studies of this nature.
Source: Scientific Journal of Dentistry
DOI: 10.15713/ins.sjod.17
Institution: Universidade de Cuiabá
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2521967237