Work

Anaplastic carcinoma of the pancreas: Case report and literature review of reported cases in Japan

Year: 2016

Type: article

Abstract: We report a case of a 64-year-old woman with anaplastic carcinoma of the pancreas (ACP) with cyst formation and review 60 ACP cases reported in Japan.In 20% of cases, laboratory tests revealed severe anemia (hemoglobin level < 10.0 g/dL) and elevated leucocyte counts (> 12000/mm 3 ), which were likely attributable to rapid tumor growth, intratumoral hemorrhage, and necrosis.Elevated serum CA19-9 levels were observed in 55% of cases.Cyst-like structures were observed on imaging in 47% of cases, and this finding appears to reflect subsequent cystic degeneration in the lesion.Macroscopically, hemorrhagic necrosis was observed in 77% of cases, and cyst formation was observed in 33% of cases.ACP should be considered when diagnosing pancreatic tumors with a cyst-like appearance, especially in the presence of severe anemia, elevated leucocyte counts, or elevated serum CA19-9 levels.

Source: World Journal of Gastroenterology

DOI: 10.3748/wjg.v22.i38.8631

Authors: Sojun Hoshimoto, Junichi Matsui, Ryohei Miyata, Yutaka Takigawa, Jun Miyauchi

Institution: Tokyo Dental College Ichikawa General Hospital

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Japan Society for the Promotion of Science