Work

Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories

Year: 2016

Type: review

Abstract: In cancers, hypoxia inducible factor 1 (HIF-1) is an over-expressed transcription factor, which regulates a large set of genes involved in tumour vascularization, metastases, and cancer stem cells (CSCs) formation and self-renewal.

Source: MedChemComm

DOI: 10.1039/c6md00432f

Authors: Anthony R. Martin, Cyril Ronco, Luc Demange, Rachid Benhida

Institutions: Centre National de la Recherche Scientifique, Université Côte d'Azur, Institut de Chimie de Nice

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2535686641

FWCI: 0.249

Cites: 273

Cited by: 27

Related to: 10