One‐Pot Preparation of Dimethyl Isosorbide from d ‐Sorbitol via Dimethyl Carbonate Chemistry
Year: 2016
Type: article
Abstract: Direct synthesis of dimethyl isosorbide (DMI) from d-sorbitol via dimethyl carbonate (DMC) chemistry is herein first reported. High yield of DMI was achieved using the nitrogen superbase 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) as catalyst and performing the reaction in a stainless steel autoclave by increasing the temperature from 90 to 200 °C. In this procedure, DMC features its full capacity acting in the different steps of the process as carboxymethylating, leaving-group (cyclization), and methylating agent; DMC is also employed as the reaction media.
Source: ChemSusChem
Authors: F. Aricò, A. S. Aldoshin, P. Tundo
Institution: Ca' Foscari University of Venice
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2560101397