Work

The Synthesis of Certain Phomentrioloxin A Analogues and Their Evaluation as Herbicidal Agents

Year: 2016

Type: article

Abstract: A series of 28 analogues of the phytotoxic geranylcyclohexentriol (-)-phomentrioloxin A (1) has been synthesized through cross-couplings of various enantiomerically pure haloconduritols or certain deoxygenated derivatives with either terminal alkynes or borylated alkenes. Some of these analogues display modest herbicidal activities, and physiological profiling studies suggest that analogue 4 inhibits photosystem II in isolated thylakoids in vitro.

Source: The Journal of Organic Chemistry

DOI: 10.1021/acs.joc.6b02372

Authors: Ehab S. Taher, Prue Guest, Amanda Benton, Xinghua Ma, Martin G. Banwell, Anthony C. Willis, Tobias Seiser, Trevor W. Newton, Johannes Hutzler

Institutions: Australian National University, BASF (Germany)

Language: English

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: Australian Research Council

OpenAlex ID: W2560816319

FWCI: 0.816

Cites: 38

Cited by: 16

Related to: 10