Work

Surgical management of chronic hyperplastic candidiasis refractory to systemic antifungal treatment

Year: 2017

Type: article

Abstract: Chronic hyperplastic candidiasis (CHC), earlier known as candidal leukoplakia, is a variant of oral candidiasis that classically presents as a white patch on the commissures of the oral mucosa and it is mostly caused by Candida albicans. Clinically, the lesions are usually asymptomatic and regress after appropriate antifungal therapy and correction of the underlying cause. If the lesions are untreated, a small portion may develop dysplasia and later progress into carcinoma. The purpose of this article is to report a case of CHC in a 57-year-old male patient with a significant smoking habit, who presented with a thick, nonscrapable, brownish-white coating on the dorsum of the tongue for 9 years. This case is of particular importance and concern because of the high risk for malignant transformation in CHC. The role of biopsy and histopathology is also stressed through this case report in arriving at a definitive diagnosis and treatment planning. Further, this case is interesting because it was refractory to local and systemic antifungal treatment and so, surgery was chosen as an alternative treatment modality considering the side effects of the prolonged use of antifungal drugs.

Source: Journal of Laboratory Physicians

DOI: 10.4103/0974-2727.199622

Authors: Neha Shah, Jay Gopal Ray, Sanchita Kundu, Divesh Sardana

Institutions: Dr. R. Ahmed Dental College and Hospital, All India Institute of Medical Sciences

Language: English

Topic: Oral Health Pathology and Treatment

Subfield: General Dentistry

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $200