Work

Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands

Year: 2017

Type: article

Abstract: Yellow foci show time dependent DNA double strand breaks in the nuclei of H358 cells treated with IC 50 concentration of [(phen) 2 Ru(tatpp)Ru(Phen) 2 ]Cl 4 .

Source: Chemical Science

DOI: 10.1039/c6sc04094b

Authors: Cynthia Griffith, Adam S. Dayoub, Thamara Jaranatne, Nagham Alatrash, Ali Mohamedi, Kenneth Abayan, Zachary S. Breitbach, Daniel W. Armstrong, Frederick M. MacDonnell

Institution: The University of Texas at Arlington

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Open Access status: diamond

Funders: National Science Foundation, Welch Foundation, Division of Chemistry

Awards: G3760746607, SusChEM: Deep Photochemical Reduction of Carbon Dioxide to Methanol, G964598076

OpenAlex ID: W2594028403

FWCI: 3.272

Cites: 141

Cited by: 48

Related to: 10