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ВЭЖХ определение, фармакокинетика и относительная биодоступность левофлоксацина производства ООО «Озон», Россия

Year: 2013

Type: article

Abstract: A simple, specific, sensitive and reproducible good method for quantitative determination of Levofloxacin in plasma using HPLC with UV-spectrophotometric detection. With this technique the pharmacokinetics and relative bioavailability of domestic generic of levofloxacin in 18 healthy volunteers after a single oral dose of 500 mg. Found that the drug being tested, levofloxacin (OOO «Ozone», Russia) is bioequivalent to the reference drugs Tavanic® («Sanofi Winthrop Industry», France).

Source: DOAJ (DOAJ: Directory of Open Access Journals)

Authors: С. Н. Кондратенко, А. К. Стародубцев, E A Senik, О. В. Дралова, С. Н. Кудинова

Institution: Sechenov University

Language: Russian

Topic: Analytical Methods in Pharmaceuticals

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2600523630

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