Work

MRI enhancement predicting fibroid volume reduction to uterine artery embolization

Year: 2017

Type: article

Abstract: Objectives: Fibroid non-enhancement is considered a relative contraindication to uterine artery embolization (UAE) for symptomatic fibroids.The purpose was to assess the impact of UAE on non-enhancing fibroids and to determine imaging predictors of fibroid shrinkage. Materials and methods:Retrospective review of all women who underwent UAE for symptomatic fibroids (5/09-7/14) and had follow-up MRI 6 months after UAE were included.There were 59 fibroids (5, non-enhancing; 54, enhancing) among 18 women with a mean age of 46 (range 40-53) years.All fibroids were assessed for size, position, enhancement on subtraction images, and Apparent Diffusion Constant (ADC).Results: Enhancing fibroids had an average decrease in diameter by 19± 3%, not significantly different that non-enhancing fibroids which decreased by 23± 6% (p=0.49).Multiple linear regression with percent change in fibroid diameter as the dependent variable and patient age, fibroid position, and pre-UAE fibroid diameter, enhancement, and ADC as independent variables, showed that ADC (p=0.04) and pre-UAE diameter (p=0.03) were the only significant independent variables.Conclusion: Pre-UAE size and ADC, but not contrast enhancement, predicted fibroid diameter reduction.Enhancing and non-enhancing fibroids had similar size reduction after UAE.Non-enhancement should not be considered a contraindication to UAE.

Source: Frontiers in Women’s Health

DOI: 10.15761/fwh.1000128

Author: Deipolyi A

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Uterine Myomas and Treatments

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2604136502