Laparoscopic liver resection for hepatocellular carcinoma in patients with cirrhosis: An Egyptian single center experience
Year: 2017
Type: article
Abstract: Background: Pure laparoscopic liver resection is a less invasive procedure than conventional liver resection for hepatic lesions.A laparoscopic approach offers the advantage of Intra-operative laparoscopic ultrasonography (IOLUS), providing better establishment of the number and location of liver tumors, as well as the condition of the liver.The aim of the study is to assess the feasibility, safety and efficacy of laparoscopic resection of hepatocellular carcinoma (HCC) in patients with liver cirrhosis.Patients and methods: Between September 2010 and January 2014, five hundred patients with liver cirrhosis and HCC were referred from the HCC clinic at the National Hepatology and Tropical Medicine Research Institute (NHTMRI).65 patients were considered suitable candidates for diagnostic laparoscopy.26 patients with HCC who fulfill the criteria of laparoscopic non-anatomical liver resection.Operation times, the duration of hospital stay, and post procedural complications were recorded.A spiral CT scan one month postoperatively was an essential part of the follow-up protocol.Results: Twenty six patients were managed entirely by laparoscopic liver resection.IOLUS examination identified previously unsuspected HCC in three patients which treated on the same session.The mean operation time was 120 ± 50 minutes; eight additional procedures were undertaken in six patients, cholecystectomy in six and adhesiolysis in two cases.Complete tumors were resected and which was subsequently documented using a spiral computed tomography (CT scan) one month after treatment.Histopathology confirmed that the entire tumour had been resected with a margin of safety. Conclusion:We have proved that a laparoscopic resection has a role in the management of HCC and it is a safe and effective technique.
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2605756072