A Case of Familial Hypercholesterolemia Receiving Simultaneous Coronary Artery Bypass Grafting and Replacement Therapy by means of an Artificial Vessel to an Abdominal Aortic Aneurysm
Year: 1990
Type: article
Study design: Case Report
Abstract: We experienced a case of familial hypercholesterolemia (FH) which received simultaneous coronary artery bypass grafting and replacement therapy of an abdominal aortic aneurysm (AAA).In 1977 FH was diagnosed in a 66-year-old man with serum cholesterol of 344mg/dl, triglyceride of 101mg/dl, and achilles tendon thickness of 14mm. In 1983 coronary angiography detected 75% stenosis in segment 7 of the left anterior descending artery (LAD). In 1985 abdominal CT scan detected AAA with a diameter of 4cm, which had increased in size by 1988.We performed re-examinations of abdominal CT scan, abdominal ultrasonography, and angiography. The results showed that the AAA had increased to a diameter of 7cm with a thrombus inside, and that the coronary artery atherosclerosis had progressed diffusely, with progression of the LAD proximal lesion resulting in an increase from 22 to 26 in the coronary sclerotic index. Accordingly, coronary artery bypass grafting to LAD segment 8 and replacement therapy of AAA were carried out simultaneously. In the case of FH, systemic atherosclerosis progresses so easily that it is imperative that close attention be paid not only to lesions in the coronary arteries but also atherosclerotic lesions elsewhere.
Institution: Kanazawa University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2606569643