Work

Spontaneous Tumor Lysis Syndrome Presenting Acute Kidney Injury with Extreme Hyperuricemia and Urinary Stone: A Rare Case of Spontaneous Tumor Lysis Syndrome

Year: 2017

Type: article

Abstract: A Rare Case of Spontaneous Tumor Lysis SyndromeTumor lysis syndrome is a serious complication of malignancy, resulting from the massive and rapid release of cellular components into the blood.Generally, it oc curs after initiation of chemotherapy.The onset of spontaneous tumor lysis synd rome (STLS) before anti-cancer treatment is rare and occurs mostly in Burkitt lymphoma and non-Hodgkin's lymphoma.There are only a few case reports in children.Here, we report a case of STLS secondary to T-cell acute lymphoblastic leukemia (ALL), which presented with urinary stone and subsequent acute kidney injury with severe hyperuricemia.Occult malignancy should be considered in case of unex plained acute kidney injury with extreme hyperuricemia.

Source: Journal of the Korean Society of Pediatric Nephrology

DOI: 10.3339/jkspn.2017.21.1.31

Authors: Seong Heon Kim, Eu Jeen Yang, Young Tak Lim, Su Young Kim

Institution: Pusan National University Children's Hospital

Language: English

Topic: Methemoglobinemia and Tumor Lysis Syndrome

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Pusan National University