Work

Key analogs of a uniquely potent synthetic vinblastine that contain modifications of the C20′ ethyl substituent

Year: 2017

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2017.05.058

Authors: Oliver Allemann, R. Matthew Cross, Manuela M. Brütsch, Aleksandar Radakovic, Dale L. Boger

Institution: Scripps Research Institute

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: American Cancer Society, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, National Institutes of Health, University of California, San Diego, Skaggs Institute for Chemical Biology, Scripps Research Institute, National Cancer Institute

Awards: G2560385436, Design and Synthesis of Novel Vinblastine Analogs for Covalent Binding to Microtubules, Antitumor Antibiotics, G9000320269

OpenAlex ID: W2616460988

FWCI: 0.995

Cites: 41

Cited by: 11

Related to: 10