Work

In vitro and in vivo investigations toward near-field microwave-based detection of melanoma

Year: 2017

Type: conference-paper

Abstract: To go toward non-invasive melanoma analysis without the requirement of biopsy, in vitro and in vivo investigations have been performed with near-field microwave sensing techniques. Preliminary dielectric study has been carried out on different types of skin crushes: normal skin and skin with a subcutaneous B16 melanoma tumor. Extracted dielectric properties permits to clearly discriminate the two samples. Based on these results, in vivo investigations-have been performed on living mice, leading to a possible microwave-based detection of melanoma, which should now be confirmed with statistical measurements. The dielectric results are in agreement with the observation through immune-analysis of increased vascular density in the presence of a tumor, i.e. water content rise.

Source: IEEE MTT-S International Microwave Biomedical Conference (IMBioC)

DOI: 10.1109/imbioc.2017.7965789

Authors: David Dubuc, Katia Grenier, Florent Morfoisse, Barbara Susini-Garmy

Institutions: Centre National de la Recherche Scientifique, Laboratoire d'Analyse et d'Architecture des Systèmes, Université de Toulouse, Inserm, Hôpital Rangueil

Language: English

Topic: Microwave Imaging and Scattering Analysis

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Centre National de la Recherche Scientifique, Institut National Du Cancer