Nonspecific Antimicrobial Resistance Status and Its Ozone Correction in Infantile Atopic Dermatitis
Year: 2014
Type: article
Study design: Clinical Trial
Abstract: Aim. To study the effect of ozone therapy on clinical indices and nonspecific antimicrobial resistance status in infantile form of atopic dermatitis. Materials and methods. 67 children (40 boys and 27 girls) aged 5-10 years with disseminated moderate atopic dermatitis were under observation. The observed patients were divided into two groups depending on the conducted therapy. Group 1 of patients with atopic dermatitis (35 patients) had generally accepted complex therapy, group 2 of patients with atopic dermatitis (32 patients) - complex treatment combined with ozone therapy. In both groups of patients with atopic dermatitis, blood serum anti-α-staphylolysine content, phagocytosis indices, toll-like receptors TLR-2 and TLR-6 were studied in the periods of exacerbation and clinical remission. Results. Ozone therapy included into complex treatment of patients with atopic dermatitis leads to activation and restoration of toll-like receptor function, normalization of blood serum anti-α-staphylolysine level, phagocytosis indices and faster occurrence of long clinical remission.
Source: Perm Medical Journal
DOI: 10.17816/pmj31124-29
Authors: Ya. Yu. Illek, Иллек Ян Юрьевич, А. В. Галанина, Галанина Алёна Васильева, Е. В. Суслова, Суслова Елена Викторовна, Г А Зайцева, Зайцева Галина Алексеевна, Н. В. Исаева, Исаева Наталья Васильевна, Е.А. Fedyaeva, Федяева Екатерина Андреевна, Valeriya Kuznetsova, Кузнецова Валентина Влвдимировна, Т.N. Rybakova, Рыбакова Татьяна Николаевна
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2736264231