Chemical and Toxicological Studies of the Phytotoxin, 6α,7β,9α-Trihydroxy-8(14), 15-isopimaradiene-20,6-γ-lactone, Produced by a Parasitic Fungus,Phomopsissp., in Wilting Pine Trees
Year: 1986
Type: article
Abstract: A phytotoxin, isopimarane diterpene y-lactol, 6a,7/?,9a-trihydroxy-8(14),1 5-isopimaradiene-20,6-y-lactone, was isolated from the culture filtrate of the fungus Phomopsis sp., which was obtained from the interior part of the trunk of most wilting Japanese red pines, Pinus densiflora Sieb.et Zucc.The stereostructure was established by X-ray crystal analysis and spectroanalysis.This y-lactol was identical with LL-S491, a fermentation product of the fungus Aspergillus chevalieri.The cytotoxic activity of the y-lactol isopimarane was the same as pentachlorophenol at 150ppm on cell cultures from Japanese red pine buds.
Institution: RIKEN
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W274040583