A simplified characterization of S-adenosyl- l -methionine-consuming enzymes with 1-Step EZ-MTase: a universal and straightforward coupled-assay for in vitro and in vivo setting
Year: 2017
Type: article
Abstract: Methyltransferases use S -adenosyl- l -methionine (SAM) to deposit methyl marks. The 1-Step EZ-MTase coupled assay is a simple tool to study many of these epigenetic ‘writers’.
Source: Chemical Science
DOI: 10.1039/c7sc02830j
Institution: Albert Einstein College of Medicine
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
Funders: American Cancer Society, American Federation for Aging Research, Vanderbilt University, University of Oregon, Vanderbilt University Medical Center, Chinese Academy of Sciences, National Institutes of Health, Albert Einstein College of Medicine, Yeshiva University, Institute of Biophysics, Chinese Academy of Sciences, National Institute on Aging, NIH Office of the Director, National Institute of General Medical Sciences
Awards: TNF alpha and IL-1 beta as pro-geronic factors in intestinal aging, Crosstalk to Histone Arginine Methylation, G2745100336, G2999951506, Console and probe upgrade for 600 MHz NMR, G5472137706, Regulation of Histone Chaperone Function by Post-Translational Modification, G8203630378, G8584415486, G9000027675
OpenAlex ID: W2741005008