Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI)
Year: 2016
Type: article
Abstract: Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR). Parametric mapping with CMR now permits the routine spatial visualization and quantification of changes in myocardial composition based on changes in T1, T2, and T2*(star) relaxation times and extracellular volume (ECV). These changes include specific disease pathways related to mainly intracellular disturbances of the cardiomyocyte (e.g., iron overload, or glycosphingolipid accumulation in Anderson-Fabry disease); extracellular disturbances in the myocardial interstitium (e.g., myocardial fibrosis or cardiac amyloidosis from accumulation of collagen or amyloid proteins, respectively); or both (myocardial edema with increased intracellular and/or extracellular water). Parametric mapping promises improvements in patient care through advances in quantitative diagnostics, inter- and intra-patient comparability, and relatedly improvements in treatment. There is a multitude of technical approaches and potential applications. This document provides a summary of the existing evidence for the clinical value of parametric mapping in the heart as of mid 2017, and gives recommendations for practical use in different clinical scenarios for scientists, clinicians, and CMR manufacturers.
Institutions: Deutsches Herzzentrum der Charité, German Centre for Cardiovascular Research, Charité - Universitätsmedizin Berlin, University College London, University of Oxford, University of Toronto, Hospital for Sick Children, St George's, University of London, National Institutes of Health, Beth Israel Deaconess Medical Center, Harvard University, University of Virginia Health System, University of Virginia Medical Center, University of Virginia, University of Pittsburgh, University of Pittsburgh Medical Center, Baker Heart and Diabetes Institute, The Alfred Hospital, University of Alberta, Karolinska University Hospital, Karolinska Institutet, Centre Hospitalier Universitaire Vaudois, University of Lausanne, University of Calgary, Heidelberg University, McGill University, Université de Montréal
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,000
Funders: University of Pittsburgh, McGill University, Deutsches Zentrum für Herz-Kreislaufforschung, University Hospitals Bristol NHS Foundation Trust, University of Alberta, National Institute for Health and Care Research, University College London, University of Oxford, Rosetrees Trust, University of Glasgow, University of Bristol, University of Toronto, Karolinska Institutet, Université de Montréal, Hospital for Sick Children, Université de Lausanne, Centre Hospitalier Universitaire Vaudois, European Association of Cardiovascular Imaging, Baker Heart and Diabetes Institute, Circle Cardiovascular Imaging, National Institutes of Health, Clinical and Translational Science Institute, University of Pittsburgh
OpenAlex ID: W2763651817