Work

Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study

Year: 2017

Type: article

Abstract: AIMTo identify the potential risk factors of cholangiocarcinoma, we determined the characteristics of cholangiocarcinoma patients among 5 different regions of Thailand. METHODSAll patients diagnosed with cholangiocarcinoma between 2008 and 2013 were identified using the Nationwide Hospital Admission Data registry (n = 39421).Baseline characteristics, comorbidities and survival were abstracted. RESULTSThe annual incidence during the study period was stable in all regions.Most patients lived in the Northeast (62.8%), followed by the North (16.9%),Central (12.3%),Bangkok (5.4%), and South (n = 2.6%) regions (P < 0.0001).Significantly more cholangiocarcinoma patients had diabetes, cirrhosis, and chronic viral hepatitis B/C infection than noncholangiocarcinoma participants (diabetes: 11.42% vs 5.28%; cirrhosis: 4.81% vs 0.92%; hepatitis B: 0.74% vs 0.12%; and hepatitis C: 0.50% vs 0.10%, P < 0.0001 for all, respectively).The overall 1-year mortality rate was 81.7%, with a stable trend over time. CONCLUSIONDiabetes and chronic liver diseases may be associated with cholangiocarcinoma in the Thai population.

Source: World Journal of Gastroenterology

DOI: 10.3748/wjg.v23.i39.7160

Authors: Roongruedee Chaiteerakij, Wirichada Pan-ngum, Kittiyod Poovorawan, Ngamphol Soonthornworasiri, Sombat Treeprasertsuk, Kamthorn Phaosawasdi