Work

Bactericidal effects of deep ultraviolet light-emitting diode for solutions during intravenous infusion

Year: 2017

Type: article

Abstract: Background: Ultraviolet irradiation is effectively used as a disinfection method for inactivating microorganisms.Methods: We investigated the bactericidal effects by irradiation with a deep-ultraviolet light-emitting diode (DUV-LED) on the causative microorganisms of catheter related blood stream infection contaminating the solution for intravenous infusion.For irradiation, prototype modules for water disinfection with a DUV-LED were used.Experiments were conducted on five kinds of microorganisms.We examined the dependence of bactericidal action on eleven solutions.Administration sets were carried out three types.Results: When the administration set JY-PB343L containing the infusion tube made of polybutadiene was used, the bactericidal action of the DUV-LED against all tested microorganisms in the physiological saline solutions was considered to be effective.We confirmed that the number of viable bacteria decreased in 5% glucose solution and electrolyte infusions with DUV-LED irradiation.Conclusions: These results indicate that the DUV-LED irradiation has bactericidal effects in glucose infusion and electrolyte infusions by irradiating via a plasticizer-free polybutadiene administration set.We consider DUV-LED irradiation to be clinically applicable.

Source: International Journal of Medical Sciences

DOI: 10.7150/ijms.22206