Worsening of Functional Mitral Regurgitation from Septal Dyssynchrony Induced by Ventricular Pacing in Ebstein's Anomaly Undergoing Percutaneous Mitral Valve Repair
Year: 2017
Type: article
Abstract: A 67-year-old male with Ebstein's anomaly and a dual-chamber pacemaker due to sick sinus syndrome was admitted to our hospital with cardiogenic shock.Echocardiography revealed severe functional mitral valve regurgitation with preserved ejection fraction.He was referred for percutaneous mitral valve repair (PMVR) for refractory shock in the setting of prohibitive surgical risk.Invasive hemodynamics obtained during PMVR revealed worsening mitral regurgitation due to septal dyssynchrony induced by the patient's permanent pacing.He underwent successful PMVR with subsequent clinical recovery.Dyssynchrony from right ventricular apical pacing may exacerbate mitral regurgitation and heart failure.PMVR with MitraClip may be a safe and effective therapeutic option in patients with refractory cariogenic shock and severe mitral regurgitation.
Authors: András Bratincsák, Elisa Rhee, Anwar Tandar, Abdulfattah Saidi, Heajung L. Nguyen, William Van Alstine, Lindsay Koren, Kimberly Stoughton, José Negrón-Garcia, Anthony Ragheb, Hannah El-Sabrout, John W. Moore, Howaida el-Said, John P. Breinholt, Jason P. Glotzbach, Frederick G.P. Welt, Vikas Sharma, Kelsee Browning, Craig H. Selzman, Abdulfattah Saidi, David A. Bull, Holly Carveth, Anwar Tandar, Marcella A. Calfon Press, Jamil A. Aboulhosn, Jeannette P. Lin, Peyman Benharash, Eric H. Yang
Institution: University of California, Los Angeles
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2777736734