Metagenome Analysis of Bodily Microbiota in a Mouse Model of Alzheimer Disease Using Bacteria-derived Membrane Vesicles in Blood
Year: 2017
Type: article
Abstract: decreased in Tg-APP/PS1 mice. A number of genus members were detected in Tg-APP/PS1 mice, but not in wild-type mice, while other genus members were detected in wild-type mice, but lost in Tg-APP/PS1 mice. The results of the present study suggest that the bodily microbiota profile is altered in Tg-APP/PS1 mice, and that blood EVs are useful for the metagenome analysis of bodily microbiota in AD.
Source: Experimental Neurobiology
Authors: Jin-Young Park, Juli Choi, Yunjin Lee, Jung-Eun Lee, Eun-Hwa Lee, Hye-Jin Kwon, Jinho Yang, Bo-Ri Jeong, Yoon-Keun Kim, Pyung-Lim Han
Institution: Ewha Womans University
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funder: Ministry of Health and Welfare
Award: G1854793927
OpenAlex ID: W2777980002