Year: 2018
Type: article
Abstract: Bats are an important natural reservoir of zoonotic viral pathogens. We previously isolated an alphaherpesvirus in fruit bats in Indonesia, and here establish the presence of viruses belonging to other taxa of the family Herpesviridae. We screened the same fruit bat population with pan-herpesvirus PCR and discovered 68 sequences of novel gammaherpesvirus, designated 'megabat gammaherpesvirus' (MgGHV). A phylogenetic analysis of approximately 3.4 kbp of continuous MgGHV sequences encompassing the glycoprotein B gene and DNA polymerase gene revealed that the MgGHV sequences are distinct from those of other reported gammaherpesviruses. Further analysis suggested the existence of co-infections of herpesviruses in Indonesian fruit bats. Our findings extend our understanding of the infectious cycles of herpesviruses in bats in Indonesia and the phylogenetic diversity of the gammaherpesviruses.
Source: Journal of Medical Microbiology
DOI: 10.1099/jmm.0.000689
Institutions: Hokkaido University, Hokkaido University International Institute for Zoonosis Control, IPB University, State University of Gorontalo, Universitas Gorontalo, Sam Ratulangi University, Hasanuddin University, Global Virus Network, Global Institution for Collaborative Research and Education, Hokkaido University
Language: English
Subfield: Animal Science and Zoology
Domain: Life Sciences
Open Access status: green
Awards: Investigation of latent pathogenic viruses in Latin America and South-eastern Asia by virome analysis, G4742956268, Analysis of relationship between protein quality control system and pathogenesis of encephalitis by flavivirus infection, チクングニアウイルスのゲノム複製を調節する新規メカニズムの解析, Investigation of the mechanism of equine herpesvirus-1 latency using mice expressing a viral receptor, G8591079338
OpenAlex ID: W2785586366