Year: 2018
Type: article
Study design: Observational Study
Abstract: Key Points Targetable ALK/ROS1 tyrosine kinase fusions were detected in JMML patients without canonical RAS pathway mutations. Genome-wide methylation analysis identified the hypermethylation profile associated with poor clinical outcome.
Source: Blood
Authors: Norihiro Murakami, Yusuke Okuno, Kenichi Yoshida, Yuichi Shiraishi, Genta Nagae, Kyogo Suzuki, Atsushi Narita, Hirotoshi Sakaguchi, Nozomu Kawashima, Xinan Wang, Yinyan Xu, Kenichi Chiba, Hiroko Tanaka, Asahito Hama, Masashi Sanada, Masafumi Ito, Masashi Hirayama, Arata Watanabe, Toshihide Ueno, Seiji Kojima, Hiroyuki Aburatani, Hiroyuki Mano, Satoru Miyano, Seishi Ogawa, Yoshiyuki Takahashi, Hideki Muramatsu
Institutions: Nagoya University, Nagoya University Hospital, Kyoto University, Research Center for Advanced Science and Technology, The University of Tokyo, The University of Tokyo, Japanese Red Cross Nagoya Daiichi Hospital, National Hospital Organization, Nagoya Medical Center, Nakadōri General Hospital, Institute of Medical Science, The University of Tokyo
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: Mechanism of choreito, a formula from Japanese Kampo medicine, for hemorrhagic cystitis, Genomewide methylation analysis of juvenile myelomonocytic leukemia, Epigenomic analysis of stem cell characteristics defining therapeutic resistance of liver cancer, Molecular basis for KIR ligand-mismatched cord blood transplantation for advanced neuroblastoma, Cellular deconvolution analysis of hepatocellular carcinoma based on the systemic epigenomic profiles, Development of a methylation analysis method for juvenile myelomonocytic leukemia using next-generation sequencing, Molecular pathogenesis in myelodysplastic syndromes (MDS)., G7540847961, Development of mutation analysis pipeline for cancer genomic medicine, Comprehensive gene analysis of clonal hematopoiesis in childhood aplastic anemia, History of Traditional Japanese Pediatrics and Their Applications to Modern Pediatrics
OpenAlex ID: W2787217613