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A Solitary Pulmonary Nodule: Pulmonary Amyloidosis

Year: 2018

Type: article

Abstract: Clinical HistoryA 67-year-old male and former smoker was admitted to the hospital because of abdominal pain.An abdominal CT scan revealed not only acute biliary pancreatitis, but also a pulmonary nodule in the right lower lobe (Figure 1).On 18-Fluoro-deoxyglucose ( 18 F-FDG) PET-CT scan the solitary pulmonary nodule posterior in the right lower lobe revealed a high 18 F-FDG-uptake (Figure 2).No enlarged or high uptake lymph nodes nor distant metastasis were seen.So far, a malignant tumor was suspected.By CT-guided biopsy of the nodule, a specimen was obtained and revealed necrotic tissue without evidence of malignancy.Mediastinoscopy for mediastinal mapping was performed.All biopsies showed normal lymph node tissue and no malignancy.Finally, a thoracoscopic right bilobectomy was performed.Histopathology of the specimens revealed an amyloid tumor with maximal diameter of 35 mm.Extensive diagnostic work-up for systemic amyloidosis remained negative.The diagnosis of pulmonary amyloidosis was confirmed.

Source: Journal of the Belgian Society of Radiology

DOI: 10.5334/jbsr.1463

Authors: Chloë Standaert, Vincent Herpels, Patrick Seynaeve

Institutions: Ghent University Hospital, AZ Groeninge

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2787508409

FWCI: 0.974

Cites: 1

Cited by: 8

Related to: 10