Year: 2017
Type: article
Study design: Case Report
Abstract: Acute invasive fungal sinusitis is a significant cause of morbidity and mortality especially in immunocompromised patients.The offending organism usually belongs to the classes Zygomycetes (Mucorspp) and Ascomycetes (Aspergillus spp).However, in the last few decades, Pseudallescheria boydii (P.boydii) has been emerging as an important human pathogen, particularly in immunocompromised hosts.[1] Although P boydii resembles Aspergillus on pathologic examination, it is crucial to identify it as it is typically resistant to amphotericin B. Patients with P boydii sinusitis should generally be treated with a combination of surgery and antifungal therapy.This is particularly important in immunocompromised patients with fungal invasion because mortality among these patients is high.Our case report highlights the importance of distinguishing P. boydii from Aspergillus in a diabetic patient with invasive fungal sinusitis to prevent irreversible complications of the disease along with a review of literature of similar cases.
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2800533149