Work

Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex

Year: 2018

Type: article

Abstract: upon opening of the nonselective CALHM1 channels. These findings reveal a distinctive organelle signature and functional organization for regulated, focal release of purinergic signals in the absence of synaptic vesicles.

Source: Science Signaling

DOI: 10.1126/scisignal.aao1815

Authors: Roman A. Romanov, Robert S. Lasher, Brigit High, Logan E. Savidge, Adam Lawson, Olga A. Rogachevskaja, Haitian Zhao, Vadim V. Rogachevsky, Marina F. Bystrova, Gleb D. Churbanov, Igor Adameyko, Tibor Harkany, Ruibiao Yang, Grahame J. Kidd, Philippe Marambaud, John C. Kinnamon, Stanislav S. Kolesnikov, Thomas E. Finger

Institutions: Russian Academy of Sciences, Immanuel Kant Baltic Federal University, Institute of Cell Biophysics, Medical University of Vienna, University of Colorado Anschutz, Feinstein Institute for Medical Research, Karolinska Institutet, Cleveland Clinic, University of Denver

Language: English

Topic: Adenosine and Purinergic Signaling

Subfield: Physiology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Russian Foundation for Basic Research, EMBO, Ministry of Education and Science of the Russian Federation, Hjärnfonden, Knut och Alice Wallenbergs Stiftelse, Forskningsrådet om Hälsa, Arbetsliv och Välfärd, Novo Nordisk Fonden, Directorate-General for Research and Innovation, European Research Council, Russian Academy of Sciences, National Institute on Aging, National Institute on Deafness and Other Communication Disorders

Awards: G1297281994, G1385202384, G2132196509, G2624750740, G3760171062, Scanning Blockface 3D EM of taste buds: a new window into functional organization, G4598883159, G6052034443, G6131231427, G6370977435, G6458342914

OpenAlex ID: W2802984476

FWCI: 8.097

Cites: 52

Cited by: 88

Related to: 10