Work

Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association

Year: 2018

Type: article

Abstract: Sign of Leser-Trélat is a rare paraneoplastic cutaneous manifestation, characterized by the sudden appearance and rapid increase in size and number of seborrheic keratoses, accompanied by pruritus. Edmund Leser and Ulysse Trélat described this sign in 1890. Since their first description, their conclusions have been considered controversial and some authors assert the absence of a causal link. It seems to be frequently associated with solid tumors and in particular gastrointestinal cancer. Here, we describe a new case associated with a cutaneous T-cell lymphoma and a partial response to extracorporeal photopheresis.

Source: Dermatopathology

DOI: 10.1159/000488982

Authors: Raphaël André, Emmanuel Laffitte, Marem Abosaleh, Bégonia Cortès, Laurence Toutous-Trellu, Gürkan Kaya

Institution: University Hospital of Geneva

Language: English

Topic: Cutaneous lymphoproliferative disorders research

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,810