Work

In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines

Year: 2018

Type: data-paper

Abstract: This article contains data on in vitro cytotoxicity activity of chloroform, methanolic and water extracts of leaf and heartwood of Caesalpinia sappan L. a medicinal plant against Breast cancer (MCF-7) and Lung cancer (A-549) cells. This data shows that Brazilin A, a natural bioactive compound in heartwood of Caesalpinia sappan L. induced cell death in breast cancer (MCF-7) cells. The therapeutic property was further proved by docking the Brazilin A molecule against BCL-2 protein (an apoptotic inhibitor) using auto dock tools.

Source: Data in Brief

DOI: 10.1016/j.dib.2018.05.050

Authors: Arunkumar Naik Bukke, Fathima Nazneen Hadi, K. Suresh Babu, P. Chandramati shankar

Institutions: Yogi Vemana University, Indian Institute of Chemical Technology

Language: English

Topic: Biological Stains and Phytochemicals

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,220