Year: 2017
Type: article
Study design: Observational Study
Abstract: Background: The aim of treatment of most psychiatric disorders is the functional improvement but some impairment persists even after remission.Cognitive and hedonic deficits persist even in remission and affect the quality of life in patients with depression and schizophrenia.The study aims to compare cognition, anhedonia and its impact on quality of life in patients with depression and schizophrenia.Methods: We interviewed 50 consecutive consenting clinically stable patients with schizophrenia (BPRS score < 31) and depressive episode (HDRS score < 08) following up in psychiatry OPD.Montreal Cognitive Assessment (MoCA) was used to assess cognition, Snaith-Hamilton Pleasure Scale (SHAPS) for anhedonia and WHOQOL-BREF for the quality of life in participants.Results: The mean age of patients with schizophrenia was 41.1±9.79 years and that for patients with the Depressive episode was 44.68±10.32years.Cognition in schizophrenia patients was significantly worse (P= 0.001) and anhedonia was better (P= 0.002) than depression, whereas the quality of life was comparable.In Schizophrenia group MoCA and SHAPS scores had a negative correlation (P= 0.034).The quality of life had significant negative correlation with anhedonia in schizophrenia as well as depression patients.Conclusion: Schizophrenia patients have higher deficits in cognition and depression sees higher hedonic deficit when compared despite being clinical stable and comparable quality of life.Anhedonia impairs quality of life in patients with depression as well as schizophrenia patients but same can't be concluded about the cognitive deficit in depression.
Institution: Cooper Hospital
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2808166296