Work

Left bundle branch block: Epidemiology, etiology, anatomic features, electrovectorcardiography, and classification proposal

Year: 2018

Type: review

Abstract: In left bundle branch block (LBBB), the ventricles are activated in a sequential manner with alterations in left ventricular mechanics, perfusion, and workload resulting in cardiac remodeling. Underlying molecular, cellular, and interstitial changes manifest clinically as changes in size, mass, geometry, and function of the heart. Cardiac remodeling is associated with progressive ventricular dysfunction, arrhythmias, and impaired prognosis. Clinical and diagnostic notions about LBBB have evolved from a simple electrocardiographic alteration to a critically important finding affecting diagnostic and clinical management of many patients. Advances in cardiac magnetic resonance imaging have significantly improved the assessment of patients with LBBB and provided additional insights into pathophysiological mechanisms of left ventricular remodeling. In this review, we will discuss the epidemiology, etiologies, and electrovectorcardiographic features of LBBB and propose a classification of the conduction disturbance.

Source: Annals of Noninvasive Electrocardiology

DOI: 10.1111/anec.12572

Authors: Andrés R. Pérez‐Riera, Raimundo Barbosa‐Barros, Marianne P. C. de Rezende Barbosa, Rodrigo Daminello‐Raimundo, Luiz C. de Abreu, Kjell Nikus

Institutions: Faculdade de Medicina do ABC, Hospital de Messejana, Tampere University Hospital, University of Tampere

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2808975670

FWCI: 0.38

Cites: 48

Cited by: 57

Related to: 10