Work

Clinical characteristic of pancreatic cancer

Year: 2018

Type: article

Abstract: Introduction: Unfortunately, the majority of cases are diagnosed at an advanced stage, where palliative chemotherapy can be administered to alleviate the symptoms and prolong life. Although pancreatic carcinogenesis has not yet been explained, familial aggregation, tobacco smoking, and hypercaloric intake are associated with pancreatic carcinogenesis. Till date, either prevention or screening programs could yet be proposed. Methods: This is a retrospective study for patients following in medical oncology department of anti-cancer center Blida between January 2010- December 2015. The aims of study are to reported the epidemiologic profile for patients with pancreatic cancer. Although pancreatic carcinogenesis has not yet been explained, familial aggregation, tobacco smoking, and hypercaloric intake are associated with pancreatic carcinogenesis. Till date, either prevention or screening programs could yet be proposed. Results: 110 patients were following in the department, the median age was 60.8 years [21-80], and sex ratio was 2. Family history of cancer was 13.7%, 30.7% Had diabetes in their antecedents, tobacco smoking was present in 46.8% of cases, 32% of obesity, the most common reasons for consultation were pain in 49.2% and jaundice in 18% with an average consultation time of 03 months. The histological type was adenocarcinoma in 95.7% of patients, stage IV and III in 78.5% and 16.3% at diagnosis. Conclusion: As the cancer of the pancreas becomes symptomatic the diagnosis is made with a late stage, which testifies to the gravity of this cancer, to improve this situation prevention keeps an important place by acting on the risk factors such as smoking and the obesity. Around the world significant efforts are being made in order to better understand pancreatic cancer. Detailed epidemiological analyses of pancreatic cancer trends and further analytical epidemiological researches will help guide future cancer control strategies.

Source: Annals of Oncology

DOI: 10.1093/annonc/mdy151.177