Year: 2018
Type: article
Abstract: A two-step isoindolone synthesis has been achieved by using an Ugi/oxidative vicarious nucleophilic substitution sequence starting from 3-nitrobenzoic acid and aromatic aldehydes. Loss of the amido group was observed as well as a further oxidative process towards hydroxyisoindolone derivatives after prolonged stirring open to the atmosphere.
Source: Synlett
Institutions: University of Sciences and Technology Houari Boumediene, Centre National de la Recherche Scientifique, École Polytechnique, École Nationale Supérieure de Techniques Avancées, Université Paris-Saclay, Laboratoire de Synthèse Organique, École Nationale Supérieure de Techniques Avancées Paris, Laboratoire de Chimie Moléculaire
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2812640551