Work

Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases

Year: 2018

Type: article

Abstract: Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields.

Source: Beilstein Journal of Organic Chemistry

DOI: 10.3762/bjoc.14.147

Authors: Svetlana O Kasatkina, Ekaterina E Stepanova, Maksim V Dmitriev, Ivan G Mokrushin, Andrey N Maslivets

Institution: Perm State University

Language: English

Topic: Chemical synthesis and pharmacological studies

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funder: Russian Science Foundation

Awards: G510649736, G8435016408