Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
Year: 2018
Type: article
Study design: Observational Study
Source: Nature Neuroscience
Authors: Andrew E. Jaffe, Richard E. Straub, Joo Heon Shin, Ran Tao, Yuan Gao, Leonardo Collado-Torres, Tony Kam-Thong, Hualin S. Xi, Jie Quan, Qiang Chen, Carlo Colantuoni, William S. Ulrich, Brady J. Maher, Amy Deep-Soboslay, Alan J. Cross, Nicholas J. Brandon, Jeffrey T. Leek, Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: University of Miami, University of Pennsylvania, Harvard University, University of Chicago, Broad Institute, Consejo Nacional de Ciencia y Tecnología, Université de Genève, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Human Genome Research Institute, NIH Office of the Director, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institute of Child Health and Human Development, Common Fund
Awards: Inhibition, Oscillations and Information Processing in Schizophrenia, Methods for high-resolution analysis of genetic effects on gene expression, G1206703408, G1217436835, G1226976794, G148749253, G1534570039, G1561323845, G1650773652, Identifying therapeutic targets for autism using Shank3-deficient mice, Identification and validation of cell specific eQTLs by Bayesian modeling, G1883398070, Using the Transcriptome for SNP and Gene Annotation, G2158443041, MODELING THE EFFECTS OF STRUCTURAL VARIATION IN GTEX DATA AND MENDELIAN DISEASE, G2651523388, G2835668146, G2877753951, White Matter Abnormalities in Schizophrenia, G3128394570, G3221727586, G32319252, Epigenetic Marks of Cocaine Addiction, G3387558946, G3443372292, G347407575, G3503792436, G3547560438, Alzheimer's Disease Research Center, G3793778294, G386607036, Genetic Regulation of Gene Expression and its Impact on Phenotypes, G4124418613, Src hypoactivity as a mediator of various molecular alterations leading to NMDAR, G4395118462, Systems approaches to link tissue-specific expression to disease, Harnessing GTEx to Create Transcriptome Knowledge and Inform Disease Biology, G4478373029, G4606556408, G4715193760, G4729234894, International Cohort Collection for Bipolar Disorder, Epistatic and Cross Tissue Analysis for Human Gene Expression Traits, Genetics Association in Schizophrenia and Other Disorders, G5097752872, G5286804338, G563538711, G5737582129, G5865458551, G5888954722, 1/3-Networks from Multidimensional Data for Schizophrenia and Related Disorders, Statistical analysis of gene expression quantitative trait loci (eQTL), Methods for high-resolution analysis of genetic effects on gene expression, G6317516893, G633025773, G634178657, G6619812508, G664140718, G6684147844, Plasma and CSF Abeta peptides in late-onset major depression, G7075004892, G7215801407, G7274654584, G7353525908, FACILITATING GTEx, DISEASE, AND GxE ANALYSES VIA FAST EXPRESSION (e)QTL MAPPING, Statistical analysis of gene expression quantitative trait loci (eQTL), CNS Mechanisms in Cocaine-Related Sudden Death, G7665525972, G7761642487, Characterizing the developing human brain transcriptome at single-base resolution, G7924626839, G7937240049, G7953026188, G7958282288, G8308451750, Clinical and Biological Studies of Early AD, G8602100876, G8644024335, G8719970897, G8788848806, G8810271873, G8906494432
OpenAlex ID: W2883175830