Work

PhoPR Contributes to Staphylococcus aureus Growth during Phosphate Starvation and Pathogenesis in an Environment-Specific Manner

Year: 2018

Type: article

Abstract: Microbial pathogens must obtain all essential nutrients, including phosphate, from the host. To optimize phosphate acquisition in diverse and dynamic environments, such as mammalian tissues, many bacteria use the PhoPR two-component system.

Source: Infection and Immunity

DOI: 10.1128/iai.00371-18

Authors: Jessica L. Kelliher, Jana N. Radin, Thomas E. Kehl-Fie

Institutions: University of Illinois Urbana-Champaign, Carl R. Woese Institute for Genomic Biology

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: March of Dimes Foundation, National Institute of Allergy and Infectious Diseases

Awards: G3274248539, Overcoming nutritional immunity: Staphylococcal adaptation to host-imposed manganese and zinc starvation, Adaptation of Staphylococcus aureus to Mn and Zn starvation imposed by the host