Coffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition
Year: 2018
Type: article
Study design: Observational Study
Abstract: The epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up. Data on coffee and tea consumption were collected through validated country-specific food questionnaires at baseline. We used Cox proportional hazards regression models to compute hazard ratios (HRs) and 95% confidence intervals (CI). Models were stratified by center and age, and adjusted for anthropometric, lifestyle and dietary factors. Median coffee and tea intake were 375 and 106 mL/day, respectively, but large variations existed by country. Comparing the highest (median of 855 mL/day) versus lowest (median of 103 mL/day) consumers of coffee and tea (450 vs. 12 mL/day) the HRs were 1.02 (95% CI, 0.94-1.09) and 0.98 (95% CI, 0.90-1.07) for risk of total prostate cancer and 0.97 (95% CI, 0.79-1.21) and 0.89 (95% CI, 0.70-1.13) for risk of fatal disease, respectively. No evidence of association was seen for consumption of total, caffeinated or decaffeinated coffee or tea and risk of total prostate cancer or cancer by stage, grade or fatality in this large cohort. Further investigations are needed to clarify whether an association exists by different preparations or by concentrations and constituents of these beverages.
Source: International Journal of Cancer
DOI: 10.1002/ijc.31634
Authors: Abhijit Sen, Nikos Papadimitriou, Pagona Lagiou, Aurora Perez‐Cornago, Ruth C. Travis, Timothy J. Key, Neil Murphy, Marc Gunter, Heinz Freisling, Ioanna Tzoulaki, David C. Muller, Amanda J. Cross, David S. Lopez, Manuela Bergmann, Heiner Boeing, Christina Bamia, Anastasia Kotanidou, Anna Karakatsani, Anne Tjønneland, Cecilie Kyrø, Malene Outzen, María‐Luisa Redondo, Valerie Cayssials, Maria‐Dolores Chirlaque, Aurelio Barricarte, Maria‐Jose Sánchez, Nerea Larrañaga, Rosario Tumino, Sara Grioni, Domenico Palli, Saverio Caini, Carlotta Sacerdote, Bas Bueno‐de‐Mesquita, Tilman Kühn, Rudolf Kaaks, Lena Maria Nilsson, Rikard Landberg, Peter Wallström, Isabel Drake, Bodil Hammer Bech, Kim Overvad, Dagfinn Aune, Kay‐Tee Khaw, Elio Riboli, Dimitrios Trichopoulos, Antonia Trichopoulou, Konstantinos K. Tsilidis
Institutions: University of Ioannina, Norwegian University of Science and Technology, Harvard University, National and Kapodistrian University of Athens, Academy of Athens, University of Oxford, Centre international de recherche sur le cancer, Imperial College London, German Institute of Human Nutrition, Hellenic Health Foundation, Evangelismos Hospital, University General Hospital Attikon, Danish Cancer Society, Gobierno del Principado de Asturias, Institut d'Investigació Biomédica de Bellvitge, Institut Català d'Oncologia, Instituto Murciano de Investigación Biosanitaria, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Universidad de Murcia, Instituto de Salud Pública de Navarra, Navarre Institute of Health Research, Universidad de Granada, Instituto de Investigación Biosanitaria de Granada, Andalusian School of Public Health, Basque Government, Fondazione IRCCS Istituto Nazionale dei Tumori, Istituto per lo Studio e la Prevenzione Oncologica, Piedmont Reference Center for Epidemiology and Cancer Prevention, University Medical Center Utrecht, University of Malaya, National Institute for Public Health and the Environment, German Cancer Research Center, Umeå University, Chalmers University of Technology, Lund University, Aarhus University, Oslo Nye Høyskole, University of Cambridge
Language: English
Topic: Coffee research and impacts
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: World Health Organization, Kræftens Bekæmpelse, Deutsches Krebsforschungszentrum, Centre International de Recherche sur le Cancer, Norges Teknisk-Naturvitenskapelige Universitet, World Cancer Research Fund International, Cancer Research UK, European Commission, Bundesministerium für Bildung und Forschung, Cancerfonden, Ministerie van Volksgezondheid, Welzijn en Sport, Vetenskapsrådet, Helse Midt-Norge, Associazione Italiana per la Ricerca sul Cancro, Deutsche Krebshilfe, Medical Research Council Canada, Hellenic Health Foundation, Medical Research Council, World Cancer Research Fund, Instituto de Salud Carlos III, European Regional Development Fund
Awards: G1032970344, G104449235, G1055973116, G1192877484, G1208621354, G1274701479, G1559294051, G1767199718, G1788645866, G1993546569, G2092716656, G2149865848, G219746026, G2235605558, G2293058991, G2336049343, G2539064604, G2541071209, G2561548287, G2590569439, G2611591051, G2933204024, G3077395769, G3084320185, G3189789075, G3217467674, G331404038, G3452641779, G3675143906, G375319704, G3980646122, G4015216323, G4049848471, G4061136640, G4089957676, G4213141252, G4213605144, G4305317257, G43956866, Health of vegetarians, G4682079261, G4811780622, G4913827001, G5004963360, G5119219000, G5375816427, G5651954792, G569447510, G569908600, G5747748742, G5750710683, G5897142711, G5990830295, G6212483348, G6320156643, G657255654, G6723261869, G6779186093, G6960682749, G7020115967, G7040807446, G7306252069, G7447125227, G7600088736, G7624991799, G7646326732, G7853538257, G7983476435, G8050896463, G8331243404, G8374761964, G8407261631, G8867963557, G8869854444, G8978728421
OpenAlex ID: W2884445197