Paget's disease in temporal bone
Year: 2018
Type: conference-paper
Study design: Case Report
Abstract: Paget's disease of bone is a focal or multifocal disease of bone remodeling in which transformed, multinucleated osteoclasts excavate bone at a greatly accelerated rate. Cycle of osteolysis and repair continue to remodel affected bone as the lesion slowly enlarges. Pagetic bone becomes highly vascular and thicker but structually weaker. These changes in turn may produce impairment of Hearing (about 30 – 50%) an vestibular symptoms (20 – 25%). Our case Report is about a 68-year-old Patient, who had since about 18 monthes Hearing loss on the left side with Tinnitus, bus without vertigo or otalgy or otorrhea. the ENT examination was inconspicuous, she had a combined Hearing loss in the tonaudiometry. Temporal bone CT Shows a sclerotic extended tumorous process in temporal bone with expansion in the sphenoid bone. Publication History Publication Date: 18 April 2018 (online) © 2018. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). Georg Thieme Verlag KG Stuttgart · New York
Source: Laryngo-Rhino-Otologie
Authors: A Alzahr, M Mansour, B Knof
Institution: Klinikum Lüdenscheid
Language: English
Topic: Bone Metabolism and Diseases
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W2884535482