Work

Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes

Year: 2018

Type: review

Abstract: The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with improved sample preparations and image analyses should be adequately combined. This mini review highlights 3D imaging used for chromosome analysis so far with future imaging directions also highlighted.

Source: Chromosoma

DOI: 10.1007/s00412-018-0678-5

Authors: Mohammed Yusuf, Kohei Kaneyoshi, Kiichi Fukui, Ian Robinson

Institutions: Aga Khan University, London Centre for Nanotechnology, University College London, The University of Osaka, Brookhaven National Laboratory

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,890