Year: 2018
Type: article
Abstract: Hepatocellular carcinoma (HCC) is one of the most common and lethal malignancies worldwide.Surgery is the mainstay of treatment, but less than 20%-30% of patients are good candidates.Actually, thermal ablation is considered the best treatment with curative intent for cirrhotic patients with unresectable HCC ≤ 3 cm.Unfortunately, radio frequency efficacy in obtaining the complete ablation of HCC nodules diminishes with increasing tumor size and local tumor progression is more frequent in larger nodules.To overcome these problems, higher-powered generators, different devices and techniques have been attempted.Furthermore, microwave ablation has been introduced with the promise of a large ablative capacity.The aim of this review is to describe the role of thermal ablation for the treatment of large unresectable HCC.
Source: Hepatoma Research
Institution: Ospedale Antonio Cardarelli
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2890177205