Availability and Speed of Data and Test Result Procurement Are Superior in Cord Blood Units
Year: 2018
Type: conference-abstract
Abstract: Cord blood has been an established source for stem cells in transplantation for hematopoietic reconstitution and other indications. DKMS Cord Blood Bank provided nearly 100 cord blood units for patients in need all over the world. The availability and speed of procurement of unit data (cord blood unit report [CBUR]), extended typing results (ET), verification/confirmatory typing results (VT/CT), and shipping of the unit itself (work-up [WU]) are sensitive and important factors with impact to the transplantation outcome. We analyzed data for requests for CBUR (n = 435), VT/CT (n = 87), and WU (n = 95) sent to DKMS CBB between 2012 and 2018. The data for VT/CT were compared with the published data of the WMDA report 2016. Ninety-seven percent of requested CBURs were sent to The German National Bone Marrow Donor Registry in 1–3 days, of which nearly 50% were reported on the same day. Only 3% were sent between days 4 and 7. WUs were facilitated within 3 days (2.1%), 4–7 days (20%), 8–14 days (45.3%), 15–21 days (20%), or >21 days (12.6%). VT/CT results could be provided from day 1 to 3 (23%), day 4 to 7 (57.5%), day 8 to 14 (14.9%), day 15 to 21 (4.6%), and day 22+ (0%). In the 2016 report, WMDA published a report rate for day 7 of 35.9% for unrelated donors and 52.5% for CBU. In comparison, DKMS CBB could provide these results in 80.5%. Many factors influence the speed of procurement of important data in preparation of transplantations. DKMS CBB could show above-average performance regarding results of requested VT/CT compared with World Marrow Donor Association data. The prompt and reliable availability of cord blood units, associated samples, and typing results represents an advantage in transplantation organization, especially in timely urgent cases.
DOI: 10.1002/sctm.12373
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,963
OpenAlex ID: W2890712466