OP07.04: The association of Crown–rump length discordance and obstetrical outcome in twin pregnancies
Year: 2018
Type: conference-abstract
Abstract: To evaluate the association of first trimester intertwin CRL discordance and adverse obstetrical outcome in both monochorionic (MC) and dichorionic (DC) diamniotic twin pregnancies. Twin pregnant women who underwent a first trimester ultrasound scan for measuring nuchal translucency between 1 January 2014 and 31 December 2016 and with known pregnancy outcomes were enrolled. They were pregnant with two live fetuses at the time of the examination between 11 and 14 weeks of gestation. Study groups were subdivided to concordant and discordant groups by the presence or the absence of ≥10% discordance in CRL measurements. A total of 621 twin pregnancies were analysed, of which 555 were DCDA twin pregnancies and 66 were MCDA twin. The CRL discordance of ≥10% was found in 86 cases (13.9%). In this study result, intertwine CRL discordance in first trimester was associated with increased risk of adverse pregnancy outcome. This tendency was more notable in chromosomal abnormalities, structural anomalies, fetal loss and body weight discrepancy. When analysis was performed separately for MC and DC twin pregnancies, the risk of these outcomes were less prominent in MC twins than in DC twins. When intertwine CRL discordance of at least 10% is diagnosed, the physician should consider fetal karyotyping especially in DC twins. A follow up ultrasound examination of both fetuses are indicated for the purpose of fetal structural evaluation. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
DOI: 10.1002/uog.19446
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2895896262